4/14/2023 0 Comments Oh inverted world shins rar fileIn cancer, loss of TSG function occurs via the deletion or inactivation of two alleles, according to Knudson’s two-hit model hypothesis. Extensive research has been conducted over the last few decades to elucidate the role of TSGs in cancer development. Cancer is a disease caused by the accumulation of genetic and epigenetic changes in two types of genes: tumor suppressor genes (TSGs) and proto-oncogenes.
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